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Time-Resolved Imaging Reveals Heterogeneous Landscapes of Nanomolar Ca(2+) in Neurons and Astroglia

Maintaining low intracellular calcium is essential to the functioning of brain cells, yet the phenomenology and mechanisms involved remain an enigma. We have advanced a two-photon excitation time-resolved imaging technique, which exploits high sensitivity of the OGB-1 fluorescence lifetime to nanomo...

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Detalles Bibliográficos
Autores principales:	Zheng, Kaiyu, Bard, Lucie, Reynolds, James P., King, Claire, Jensen, Thomas P., Gourine, Alexander V., Rusakov, Dmitri A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2015
Materias:	NeuroResource
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622934/ https://www.ncbi.nlm.nih.gov/pubmed/26494277 http://dx.doi.org/10.1016/j.neuron.2015.09.043

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