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Physical stability of drugs after storage above and below the glass transition temperature: Relationship to glass-forming ability

Amorphous materials are inherently unstable and tend to crystallize upon storage. In this study, we investigated the extent to which the physical stability and inherent crystallization tendency of drugs are related to their glass-forming ability (GFA), the glass transition temperature (T(g)) and the...

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Detalles Bibliográficos
Autores principales: Alhalaweh, Amjad, Alzghoul, Ahmad, Mahlin, Denny, Bergström, Christel A.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622963/
https://www.ncbi.nlm.nih.gov/pubmed/26341321
http://dx.doi.org/10.1016/j.ijpharm.2015.08.101