Cargando…

Studies on the catalytic domains of multiple JmjC oxygenases using peptide substrates

The JmjC-domain-containing 2-oxoglutarate-dependent oxygenases catalyze protein hydroxylation and N(ε)-methyllysine demethylation via hydroxylation. A subgroup of this family, the JmjC lysine demethylases (JmjC KDMs) are involved in histone modifications at multiple sites. There are conflicting repo...

Descripción completa

Detalles Bibliográficos
Autores principales: Williams, Sophie T, Walport, Louise J, Hopkinson, Richard J, Madden, Sarah K, Chowdhury, Rasheduzzaman, Schofield, Christopher J, Kawamura, Akane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623018/
https://www.ncbi.nlm.nih.gov/pubmed/25625844
http://dx.doi.org/10.4161/15592294.2014.983381