Potent neutralizing anti-CD1d antibody reduces lung cytokine release in primate asthma model

CD1d is a receptor on antigen-presenting cells involved in triggering cell populations, particularly natural killer T (NKT) cells, to release high levels of cytokines. NKT cells are implicated in asthma pathology and blockade of the CD1d/NKT cell pathway may have therapeutic potential. We developed...

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Detalles Bibliográficos
Autores principales: Nambiar, Jonathan, Clarke, Adam W, Shim, Doris, Mabon, David, Tian, Chen, Windloch, Karolina, Buhmann, Chris, Corazon, Beau, Lindgren, Matilda, Pollard, Matthew, Domagala, Teresa, Poulton, Lynn, Doyle, Anthony G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623119/
https://www.ncbi.nlm.nih.gov/pubmed/25751125
http://dx.doi.org/10.1080/19420862.2015.1016693

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