Cargando…

Primary Spinal Cord Oligodendroglioma with Postoperative Adjuvant Radiotherapy: A Case Report

Primary spinal cord oligodendrogliomas are rare tumors comprising two percent of all spinal cord tumors. Although a treatment guideline has yet to be established, maximal surgical resection is primary in the treatment of spinal cord oligodendrogliomas. Adjuvant radiotherapy has remained controversia...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuh, Woon Tak, Chung, Chun Kee, Park, Sung-Hye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Spinal Neurosurgery Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623174/
https://www.ncbi.nlm.nih.gov/pubmed/26512274
http://dx.doi.org/10.14245/kjs.2015.12.3.160
_version_ 1782397650289557504
author Yuh, Woon Tak
Chung, Chun Kee
Park, Sung-Hye
author_facet Yuh, Woon Tak
Chung, Chun Kee
Park, Sung-Hye
author_sort Yuh, Woon Tak
collection PubMed
description Primary spinal cord oligodendrogliomas are rare tumors comprising two percent of all spinal cord tumors. Although a treatment guideline has yet to be established, maximal surgical resection is primary in the treatment of spinal cord oligodendrogliomas. Adjuvant radiotherapy has remained controversial, and it is unclear whether chemotherapy adds any benefit. In this case report, the authors present a 24-year-old male who had a seven-year history of left leg weakness and a radiating pain in both legs. Magnetic resonance image (MRI) showed an intramedullary mass at the T4-T8 level. He underwent subtotal removal of the tumor and pathologic diagnosis revealed a WHO grade II oligodendroglioma. The patient was treated with radiotherapy postoperatively and followed up with MRI annually. Clinical and radiological status of the patient had been stationary for four years after the surgery. The five-year follow-up MRI showed an increase in the size and extent of the residual tumor. Despite radiological progression, considering that symptoms and the performance status of the patient had remained unchanged, further treatment has not been performed. Given the clinical outcome of this patient, close observation after subtotal removal with adjuvant radiotherapy is one of the acceptable treatment options for WHO grade II spinal cord oligodendrogliomas.
format Online
Article
Text
id pubmed-4623174
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher The Korean Spinal Neurosurgery Society
record_format MEDLINE/PubMed
spelling pubmed-46231742015-10-28 Primary Spinal Cord Oligodendroglioma with Postoperative Adjuvant Radiotherapy: A Case Report Yuh, Woon Tak Chung, Chun Kee Park, Sung-Hye Korean J Spine Case Report Primary spinal cord oligodendrogliomas are rare tumors comprising two percent of all spinal cord tumors. Although a treatment guideline has yet to be established, maximal surgical resection is primary in the treatment of spinal cord oligodendrogliomas. Adjuvant radiotherapy has remained controversial, and it is unclear whether chemotherapy adds any benefit. In this case report, the authors present a 24-year-old male who had a seven-year history of left leg weakness and a radiating pain in both legs. Magnetic resonance image (MRI) showed an intramedullary mass at the T4-T8 level. He underwent subtotal removal of the tumor and pathologic diagnosis revealed a WHO grade II oligodendroglioma. The patient was treated with radiotherapy postoperatively and followed up with MRI annually. Clinical and radiological status of the patient had been stationary for four years after the surgery. The five-year follow-up MRI showed an increase in the size and extent of the residual tumor. Despite radiological progression, considering that symptoms and the performance status of the patient had remained unchanged, further treatment has not been performed. Given the clinical outcome of this patient, close observation after subtotal removal with adjuvant radiotherapy is one of the acceptable treatment options for WHO grade II spinal cord oligodendrogliomas. The Korean Spinal Neurosurgery Society 2015-09 2015-09-30 /pmc/articles/PMC4623174/ /pubmed/26512274 http://dx.doi.org/10.14245/kjs.2015.12.3.160 Text en Copyright © 2015 The Korean Spinal Neurosurgery Society http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Yuh, Woon Tak
Chung, Chun Kee
Park, Sung-Hye
Primary Spinal Cord Oligodendroglioma with Postoperative Adjuvant Radiotherapy: A Case Report
title Primary Spinal Cord Oligodendroglioma with Postoperative Adjuvant Radiotherapy: A Case Report
title_full Primary Spinal Cord Oligodendroglioma with Postoperative Adjuvant Radiotherapy: A Case Report
title_fullStr Primary Spinal Cord Oligodendroglioma with Postoperative Adjuvant Radiotherapy: A Case Report
title_full_unstemmed Primary Spinal Cord Oligodendroglioma with Postoperative Adjuvant Radiotherapy: A Case Report
title_short Primary Spinal Cord Oligodendroglioma with Postoperative Adjuvant Radiotherapy: A Case Report
title_sort primary spinal cord oligodendroglioma with postoperative adjuvant radiotherapy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623174/
https://www.ncbi.nlm.nih.gov/pubmed/26512274
http://dx.doi.org/10.14245/kjs.2015.12.3.160
work_keys_str_mv AT yuhwoontak primaryspinalcordoligodendrogliomawithpostoperativeadjuvantradiotherapyacasereport
AT chungchunkee primaryspinalcordoligodendrogliomawithpostoperativeadjuvantradiotherapyacasereport
AT parksunghye primaryspinalcordoligodendrogliomawithpostoperativeadjuvantradiotherapyacasereport