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Suppression of MAPK attenuates neuronal cell death induced by activated glia-conditioned medium in alpha-synuclein overexpressing SH-SY5Y cells

BACKGROUND: Parkinson’s disease (PD) is a neurodegenerative disease with characteristics and symptoms that are well defined. Nevertheless, its aetiology remains unknown. PD is characterized by the presence of Lewy bodies inside neurons. α-Synuclein (α-syn) is a soluble protein present in the pre-syn...

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Detalles Bibliográficos
Autores principales:	Yshii, Lidia M., Denadai-Souza, Alexandre, Vasconcelos, Andrea R., Avellar, Maria Christina W., Scavone, Cristoforo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623263/ https://www.ncbi.nlm.nih.gov/pubmed/26502720 http://dx.doi.org/10.1186/s12974-015-0412-7

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