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Differential post-transcriptional regulation of IL-10 by TLR2 and TLR4-activated macrophages

The activation of TLRs by microbial molecules triggers intracellular-signaling cascades and the expression of cytokines such as IL-10. Il10 expression is tightly controlled to ensure effective immune responses, while preventing pathology. Maximal TLR-induction of Il10 transcription in macrophages re...

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Detalles Bibliográficos
Autores principales:	Teixeira-Coelho, Maria, Guedes, Joana, Ferreirinha, Pedro, Howes, Ashleigh, Pedrosa, Jorge, Rodrigues, Fernando, Lai, Wi S, Blackshear, Perry J, O'Garra, Anne, Castro, António G, Saraiva, Margarida
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Molecular Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623319/ https://www.ncbi.nlm.nih.gov/pubmed/24227629 http://dx.doi.org/10.1002/eji.201343734

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