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Role of TGFβ signaling in the pathogenesis of Alzheimer’s disease

Aging is the main risk factor for Alzheimer’s disease (AD); being associated with conspicuous changes on microglia activation. Aged microglia exhibit an increased expression of cytokines, exacerbated reactivity to various stimuli, oxidative stress, and reduced phagocytosis of β-amyloid (Aβ). Whereas...

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Detalles Bibliográficos
Autores principales:	von Bernhardi, Rommy, Cornejo, Francisca, Parada, Guillermo E., Eugenín, Jaime
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623426/ https://www.ncbi.nlm.nih.gov/pubmed/26578886 http://dx.doi.org/10.3389/fncel.2015.00426

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