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Messenger RNA-based therapeutics for the treatment of apoptosis-associated diseases
Gene therapy is a promising approach for treating diseases that are closely associated with excessive apoptosis, because the gene can effectively and sustainably introduce anti-apoptotic factors into cells. However, DNA delivery poses the risk of random genomic integration, leading to overexpression...
Autores principales: | Matsui, Akitsugu, Uchida, Satoshi, Ishii, Takehiko, Itaka, Keiji, Kataoka, Kazunori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623474/ https://www.ncbi.nlm.nih.gov/pubmed/26507781 http://dx.doi.org/10.1038/srep15810 |
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