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A systematic study of normalization methods for Infinium 450K methylation data using whole-genome bisulfite sequencing data

DNA methylation plays an important role in disease etiology. The Illumina Infinium HumanMethylation450 (450K) BeadChip is a widely used platform in large-scale epidemiologic studies. This platform can efficiently and simultaneously measure methylation levels at ∼480,000 CpG sites in the human genome...

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Detalles Bibliográficos
Autores principales:	Wang, Ting, Guan, Weihua, Lin, Jerome, Boutaoui, Nadia, Canino, Glorisa, Luo, Jianhua, Celedón, Juan Carlos, Chen, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623491/ https://www.ncbi.nlm.nih.gov/pubmed/26036609 http://dx.doi.org/10.1080/15592294.2015.1057384

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