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Metabolic profiling reveals potential metabolic markers associated with Hypoxia Inducible Factor-mediated signalling in hypoxic cancer cells

Hypoxia inducible factors (HIFs) plays an important role in oxygen compromised environments and therefore in tumour survival. In this research, metabolomics has been applied to study HIFs metabolic function in two cell models: mouse hepatocellular carcinoma and human colon carcinoma, whereby the met...

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Detalles Bibliográficos
Autores principales:	Armitage, Emily G., Kotze, Helen L., Allwood, J. William, Dunn, Warwick B., Goodacre, Royston, Williams, Kaye J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623531/ https://www.ncbi.nlm.nih.gov/pubmed/26508589 http://dx.doi.org/10.1038/srep15649

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