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Osmotic Edema Rapidly Increases Neuronal Excitability Through Activation of NMDA Receptor-Dependent Slow Inward Currents in Juvenile and Adult Hippocampus
Cellular edema (cell swelling) is a principal component of numerous brain disorders including ischemia, cortical spreading depression, hyponatremia, and epilepsy. Cellular edema increases seizure-like activity in vitro and in vivo, largely through nonsynaptic mechanisms attributable to reduction of...
Autores principales: | Lauderdale, Kelli, Murphy, Thomas, Tung, Tina, Davila, David, Binder, Devin K., Fiacco, Todd A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623564/ https://www.ncbi.nlm.nih.gov/pubmed/26489684 http://dx.doi.org/10.1177/1759091415605115 |
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