Cargando…

Genetic and epigenetic variation in the lineage specification of regulatory T cells

Regulatory T (Treg) cells, which suppress autoimmunity and other inflammatory states, are characterized by a distinct set of genetic elements controlling their gene expression. However, the extent of genetic and associated epigenetic variation in the Treg cell lineage and its possible relation to di...

Descripción completa

Detalles Bibliográficos
Autores principales: Arvey, Aaron, van der Veeken, Joris, Plitas, George, Rich, Stephen S, Concannon, Patrick, Rudensky, Alexander Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623597/
https://www.ncbi.nlm.nih.gov/pubmed/26510014
http://dx.doi.org/10.7554/eLife.07571