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Inhibition of Proteasome Activity by Low-dose Bortezomib Attenuates Angiotensin II-induced Abdominal Aortic Aneurysm in Apo E(−/−) Mice

Abdominal aortic aneurysm (AAA) is a leading cause of sudden death in aged people. Activation of ubiquitin proteasome system (UPS) plays a critical role in the protein quality control and various diseases. However, the functional role of UPS in AAA formation remains unclear. In this study, we found...

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Detalles Bibliográficos
Autores principales:	Ren, Hualiang, Li, Fangda, Tian, Cui, Nie, Hao, Wang, Lei, Li, Hui-Hua, Zheng, Yuehong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623715/ https://www.ncbi.nlm.nih.gov/pubmed/26508670 http://dx.doi.org/10.1038/srep15730

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