A feedback regulatory loop involving p53/miR-200 and growth hormone endocrine axis controls embryo size of zebrafish

In vertebrates, growth hormone/insulin-like growth factor (GH/IGF) axis signaling plays a critical role in regulating somatic growth. Understanding the direct upstream regulators of GH/IGF axis remains a major challenge. Our studies of the zebrafish reveal that the conserved miR-200 family members a...

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Detalles Bibliográficos
Autores principales: Jing, Jing, Xiong, Shuting, Li, Zhi, Wu, Junjie, Zhou, Li, Gui, Jian-Fang, Mei, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623745/
https://www.ncbi.nlm.nih.gov/pubmed/26507500
http://dx.doi.org/10.1038/srep15906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623745/
https://www.ncbi.nlm.nih.gov/pubmed/26507500
http://dx.doi.org/10.1038/srep15906

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