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A feedback regulatory loop involving p53/miR-200 and growth hormone endocrine axis controls embryo size of zebrafish
In vertebrates, growth hormone/insulin-like growth factor (GH/IGF) axis signaling plays a critical role in regulating somatic growth. Understanding the direct upstream regulators of GH/IGF axis remains a major challenge. Our studies of the zebrafish reveal that the conserved miR-200 family members a...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623745/ https://www.ncbi.nlm.nih.gov/pubmed/26507500 http://dx.doi.org/10.1038/srep15906 |