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Comparing the Therapeutic Effectiveness of N-acetylcysteine with the Combination of N-acetyl Cysteine and Cimetidine in Acute Acetaminophen Toxicity: A Double-Blinded Clinical Trial

BACKGROUND: N-acetylcysteine (NAC) has been used as a classic treatment for hepatotoxicity induced by N-acetyl-p-benzoquinone imine (NAPQI) as a metabolite of acetaminophen. However, cimetidine theoretically can reduce the production of toxic metabolites through the inhibition of cytochrome p450, an...

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Detalles Bibliográficos
Autores principales:	Ebrahimi, Mohsen, Mousavi, Seyed Reza, Toussi, Alireza Ghassemi, Reihani, Hamidreza, Bagherian, Farhad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Electronic physician 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623788/ https://www.ncbi.nlm.nih.gov/pubmed/26516435 http://dx.doi.org/10.14661/1310

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