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High Resolution Structural Characterization of Aβ(42) Amyloid Fibrils by Magic Angle Spinning NMR
[Image: see text] The presence of amyloid plaques composed of amyloid beta (Aβ) fibrils is a hallmark of Alzheimer’s disease (AD). The Aβ peptide is present as several length variants with two common alloforms consisting of 40 and 42 amino acids, denoted Aβ(1–40) and Aβ(1–42), respectively. While th...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623963/ https://www.ncbi.nlm.nih.gov/pubmed/26001057 http://dx.doi.org/10.1021/jacs.5b03997 |