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pMD-Membrane: A Method for Ligand Binding Site Identification in Membrane-Bound Proteins
Probe-based or mixed solvent molecular dynamics simulation is a useful approach for the identification and characterization of druggable sites in drug targets. However, thus far the method has been applied only to soluble proteins. A major reason for this is the potential effect of the probe molecul...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623977/ https://www.ncbi.nlm.nih.gov/pubmed/26506102 http://dx.doi.org/10.1371/journal.pcbi.1004469 |