Modulation of Closed−State Inactivation in Kv2.1/Kv6.4 Heterotetramers as Mechanism for 4−AP Induced Potentiation

The voltage−gated K(+) (Kv) channel subunits Kv2.1 and Kv2.2 are expressed in almost every tissue. The diversity of Kv2 current is increased by interacting with the electrically silent Kv (KvS) subunits Kv5−Kv6 and Kv8−Kv9, into functional heterotetrameric Kv2/KvS channels. These Kv2/KvS channels po...

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Detalles Bibliográficos
Autores principales: Stas, Jeroen I., Bocksteins, Elke, Labro, Alain J., Snyders, Dirk J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623978/
https://www.ncbi.nlm.nih.gov/pubmed/26505474
http://dx.doi.org/10.1371/journal.pone.0141349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623978/
https://www.ncbi.nlm.nih.gov/pubmed/26505474
http://dx.doi.org/10.1371/journal.pone.0141349

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