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Strategies and Advancement in Antibody-Drug Conjugate Optimization for Targeted Cancer Therapeutics

Antibody-drug conjugates utilize the antibody as a delivery vehicle for highly potent cytotoxic molecules with specificity for tumor-associated antigens for cancer therapy. Critical parameters that govern successful antibody-drug conjugate development for clinical use include the selection of the tu...

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Detalles Bibliográficos
Autores principales: Kim, Eunhee G., Kim, Kristine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624065/
https://www.ncbi.nlm.nih.gov/pubmed/26535074
http://dx.doi.org/10.4062/biomolther.2015.116