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Strategies and Advancement in Antibody-Drug Conjugate Optimization for Targeted Cancer Therapeutics
Antibody-drug conjugates utilize the antibody as a delivery vehicle for highly potent cytotoxic molecules with specificity for tumor-associated antigens for cancer therapy. Critical parameters that govern successful antibody-drug conjugate development for clinical use include the selection of the tu...
Autores principales: | Kim, Eunhee G., Kim, Kristine M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624065/ https://www.ncbi.nlm.nih.gov/pubmed/26535074 http://dx.doi.org/10.4062/biomolther.2015.116 |
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