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Screening of Transcription Factors Involved in Fetal Hemoglobin Regulation Using Phylogenetic Footprinting
Fetal hemoglobin (Hb F) is an important genetic modulator of the beta-hemoglobinopathies. The regulation of Hb F levels is influenced by transcription factors. We used phylogenetic footprinting to screen transcription factors that have binding sites in HBG1 and HBG2 genes’ noncoding regions in order...
Autores principales: | de Souza Carrocini, Gisele Cristine, Venancio, Larissa Paola Rodrigues, Bonini-Domingos, Claudia Regina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624090/ https://www.ncbi.nlm.nih.gov/pubmed/26543346 http://dx.doi.org/10.4137/EBO.S15364 |
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