The potential of a multiplex high-throughput molecular assay for early detection of first and second line tuberculosis drug resistance mutations to improve infection control and reduce costs: a decision analytical modeling study

BACKGROUND: Molecular resistance detection (MRD) of resistance to second-line anti-tuberculous drugs provides faster results than phenotypic tests, may shorten treatment and allow earlier separation among patients with and without second-line drug resistance. METHODS: In a decision-analytical model...

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Detalles Bibliográficos
Autores principales: van’t Hoog, AH, Bergval, I., Tukvadze, N., Sengstake, S., Aspindzelashvili, R., Anthony, RM, Cobelens, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624169/
https://www.ncbi.nlm.nih.gov/pubmed/26503434
http://dx.doi.org/10.1186/s12879-015-1205-4

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