Insulin enhances striatal dopamine release by activating cholinergic interneurons and thereby signals reward

Insulin activates insulin receptors (InsRs) in the hypothalamus to signal satiety after a meal. However, the rising incidence of obesity, which results in chronically elevated insulin levels, implies that insulin may also act in brain centres that regulate motivation and reward. We report here that...

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Detalles Bibliográficos
Autores principales: Stouffer, Melissa A., Woods, Catherine A., Patel, Jyoti C., Lee, Christian R., Witkovsky, Paul, Bao, Li, Machold, Robert P., Jones, Kymry T., de Vaca, Soledad Cabeza, Reith, Maarten E. A., Carr, Kenneth D., Rice, Margaret E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624275/
https://www.ncbi.nlm.nih.gov/pubmed/26503322
http://dx.doi.org/10.1038/ncomms9543

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