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Real-Time Observation of the Initiation of RNA Polymerase II Transcription
Biochemical and structural studies have shown that the initiation of RNA polymerase II (pol II) transcription proceeds in the following stages: assembly of pol II with general transcription factors (GTFs) and promoter DNA in a “closed” preinitiation complex (PIC)(1,2); unwinding about 15 bp of the p...
Autores principales: | Fazal, Furqan M., Meng, Cong A., Murakami, Kenji, Kornberg, Roger D., Block, Steven M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624315/ https://www.ncbi.nlm.nih.gov/pubmed/26331540 http://dx.doi.org/10.1038/nature14882 |
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