Efficient and quantitative high-throughput transfer RNA sequencing

Despite its biological importance, transfer RNA (tRNA) could not be adequately sequenced by standard methods due to abundant post-transcriptional modifications and stable structure, which interfere with cDNA synthesis. We achieve efficient and quantitative tRNA sequencing using engineered demethylas...

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Detalles Bibliográficos
Autores principales: Zheng, Guanqun, Qin, Yidan, Clark, Wesley C., Dai, Qing, Yi, Chengqi, He, Chuan, Lambowitz, Alan M., Pan, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624326/
https://www.ncbi.nlm.nih.gov/pubmed/26214130
http://dx.doi.org/10.1038/nmeth.3478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624326/
https://www.ncbi.nlm.nih.gov/pubmed/26214130
http://dx.doi.org/10.1038/nmeth.3478

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