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Strategies for Understanding and Reducing the Plasmodium vivax and Plasmodium ovale Hypnozoite Reservoir in Papua New Guinean Children: A Randomised Placebo-Controlled Trial and Mathematical Model
BACKGROUND: The undetectable hypnozoite reservoir for relapsing Plasmodium vivax and P. ovale malarias presents a major challenge for malaria control and elimination in endemic countries. This study aims to directly determine the contribution of relapses to the burden of P. vivax and P. ovale infect...
Autores principales: | Robinson, Leanne J., Wampfler, Rahel, Betuela, Inoni, Karl, Stephan, White, Michael T., Li Wai Suen, Connie S. N., Hofmann, Natalie E., Kinboro, Benson, Waltmann, Andreea, Brewster, Jessica, Lorry, Lina, Tarongka, Nandao, Samol, Lornah, Silkey, Mariabeth, Bassat, Quique, Siba, Peter M., Schofield, Louis, Felger, Ingrid, Mueller, Ivo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624431/ https://www.ncbi.nlm.nih.gov/pubmed/26505753 http://dx.doi.org/10.1371/journal.pmed.1001891 |
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