Neural Mechanisms Supporting Maladaptive Food Choices in Anorexia Nervosa

People routinely make poor choices, despite knowledge of negative consequences. We found that individuals with Anorexia Nervosa, who make maladaptive food choices to the point of starvation, engaged the dorsal striatum more than healthy controls when making choices about what to eat, and that activi...

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Detalles Bibliográficos
Autores principales: Foerde, Karin, Steinglass, Joanna, Shohamy, Daphna, Walsh, B. Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624561/
https://www.ncbi.nlm.nih.gov/pubmed/26457555
http://dx.doi.org/10.1038/nn.4136
Descripción
Sumario:People routinely make poor choices, despite knowledge of negative consequences. We found that individuals with Anorexia Nervosa, who make maladaptive food choices to the point of starvation, engaged the dorsal striatum more than healthy controls when making choices about what to eat, and that activity in fronto-striatal circuits was correlated with their actual food consumption in a meal the next day.

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