Neural Mechanisms Supporting Maladaptive Food Choices in Anorexia Nervosa

People routinely make poor choices, despite knowledge of negative consequences. We found that individuals with Anorexia Nervosa, who make maladaptive food choices to the point of starvation, engaged the dorsal striatum more than healthy controls when making choices about what to eat, and that activi...

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Detalles Bibliográficos
Autores principales: Foerde, Karin, Steinglass, Joanna, Shohamy, Daphna, Walsh, B. Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624561/
https://www.ncbi.nlm.nih.gov/pubmed/26457555
http://dx.doi.org/10.1038/nn.4136
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author Foerde, Karin
Steinglass, Joanna
Shohamy, Daphna
Walsh, B. Timothy
author_facet Foerde, Karin
Steinglass, Joanna
Shohamy, Daphna
Walsh, B. Timothy
author_sort Foerde, Karin
collection PubMed
description People routinely make poor choices, despite knowledge of negative consequences. We found that individuals with Anorexia Nervosa, who make maladaptive food choices to the point of starvation, engaged the dorsal striatum more than healthy controls when making choices about what to eat, and that activity in fronto-striatal circuits was correlated with their actual food consumption in a meal the next day.
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spelling pubmed-46245612016-05-01 Neural Mechanisms Supporting Maladaptive Food Choices in Anorexia Nervosa Foerde, Karin Steinglass, Joanna Shohamy, Daphna Walsh, B. Timothy Nat Neurosci Article People routinely make poor choices, despite knowledge of negative consequences. We found that individuals with Anorexia Nervosa, who make maladaptive food choices to the point of starvation, engaged the dorsal striatum more than healthy controls when making choices about what to eat, and that activity in fronto-striatal circuits was correlated with their actual food consumption in a meal the next day. 2015-10-12 2015-11 /pmc/articles/PMC4624561/ /pubmed/26457555 http://dx.doi.org/10.1038/nn.4136 Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Foerde, Karin
Steinglass, Joanna
Shohamy, Daphna
Walsh, B. Timothy
Neural Mechanisms Supporting Maladaptive Food Choices in Anorexia Nervosa
title Neural Mechanisms Supporting Maladaptive Food Choices in Anorexia Nervosa
title_full Neural Mechanisms Supporting Maladaptive Food Choices in Anorexia Nervosa
title_fullStr Neural Mechanisms Supporting Maladaptive Food Choices in Anorexia Nervosa
title_full_unstemmed Neural Mechanisms Supporting Maladaptive Food Choices in Anorexia Nervosa
title_short Neural Mechanisms Supporting Maladaptive Food Choices in Anorexia Nervosa
title_sort neural mechanisms supporting maladaptive food choices in anorexia nervosa
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624561/
https://www.ncbi.nlm.nih.gov/pubmed/26457555
http://dx.doi.org/10.1038/nn.4136
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