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TIM-1 acts a dual-attachment receptor for Ebolavirus by interacting directly with viral GP and the PS on the viral envelope
Ebolavirus can cause hemorrhagic fever in humans with a mortality rate of 50%–90%. Currently, no approved vaccines and antiviral therapies are available. Human TIM1 is considered as an attachment factor for EBOV, enhancing viral infection through interaction with PS located on the viral envelope. Ho...
Autores principales: | Yuan, Shuai, Cao, Lei, Ling, Hui, Dang, Minghao, Sun, Yao, Zhang, Xuyuan, Chen, Yutao, Zhang, Liguo, Su, Dan, Wang, Xiangxi, Rao, Zihe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624681/ https://www.ncbi.nlm.nih.gov/pubmed/26487564 http://dx.doi.org/10.1007/s13238-015-0220-y |
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