Co-expression of Interleukin-15 Enhances the Protective Immune Responses Induced by Immunization with a Murine Malaria MVA-Based Vaccine Encoding the Circumsporozoite Protein

Malaria remains a major global public health problem with an estimated 200 million cases detected in 2012. Although the most advanced candidate malaria vaccine (RTS,S) has shown promise in clinical trials, its modest efficacy and durability have created uncertainty about the impact of RTS,S immuniza...

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Detalles Bibliográficos
Autores principales: Parra, Marcela, Liu, Xia, Derrick, Steven C., Yang, Amy, Molina-Cruz, Alvaro, Barillas-Mury, Carolina, Zheng, Hong, Thao Pham, Phuong, Sedegah, Martha, Belmonte, Arnel, Litilit, Dianne D., Waldmann, Thomas A., Kumar, Sanjai, Morris, Sheldon L., Perera, Liyanage P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624717/
https://www.ncbi.nlm.nih.gov/pubmed/26505634
http://dx.doi.org/10.1371/journal.pone.0141141

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