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Association of Germline CHEK2 Gene Variants with Risk and Prognosis of Non-Hodgkin Lymphoma

The checkpoint kinase 2 gene (CHEK2) codes for the CHK2 protein, an important mediator of the DNA damage response pathway. The CHEK2 gene has been recognized as a multi-cancer susceptibility gene; however, its role in non-Hodgkin lymphoma (NHL) remains unclear. We performed mutation analysis of the...

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Detalles Bibliográficos
Autores principales:	Havranek, Ondrej, Kleiblova, Petra, Hojny, Jan, Lhota, Filip, Soucek, Pavel, Trneny, Marek, Kleibl, Zdenek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624763/ https://www.ncbi.nlm.nih.gov/pubmed/26506619 http://dx.doi.org/10.1371/journal.pone.0140819

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