Cargando…
ADNP: in search for molecular mechanisms and innovative therapeutic strategies for frontotemporal degeneration
Activity-dependent neuroprotective protein (ADNP) is deregulated in Alzheimer's disease (AD) and in schizophrenia and mutated in autism. In mice, ADNP is essential for brain formation and ADNP haploinsufficiency is associated with cognitive and social deficits and tauopathy. Tauopathy, a major...
Autores principales: | Gozes, Illana, Ivashko-Pachima, Yanina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624849/ https://www.ncbi.nlm.nih.gov/pubmed/26578950 http://dx.doi.org/10.3389/fnagi.2015.00205 |
Ejemplares similares
-
ADNP, a Microtubule Interacting Protein, Provides Neuroprotection Through End Binding Proteins and Tau: An Amplifier Effect
por: Gozes, Illana, et al.
Publicado: (2018) -
The ADNP Derived Peptide, NAP Modulates the Tubulin Pool: Implication for Neurotrophic and Neuroprotective Activities
por: Oz, Saar, et al.
Publicado: (2012) -
Distinct Impairments Characterizing Different ADNP Mutants Reveal Aberrant Cytoplasmic-Nuclear Crosstalk
por: Ganaiem, Maram, et al.
Publicado: (2022) -
NAP (Davunetide): The Neuroprotective ADNP Drug Candidate Penetrates Cell Nuclei Explaining Pleiotropic Mechanisms
por: Ganaiem, Maram, et al.
Publicado: (2023) -
A Novel Microtubule-Tau Association Enhancer and Neuroprotective Drug Candidate: Ac-SKIP
por: Ivashko-Pachima, Yanina, et al.
Publicado: (2019)