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Effect of Hyperoxia on Retinoid Metabolism and Retinoid Receptor Expression in the Lungs of Newborn Mice

BACKGROUND: Preterm newborns that receive oxygen therapy often develop bronchopulmonary dysplasia (BPD), which is abnormal lung development characterized by impaired alveologenesis. Oxygen-mediated injury is thought to disrupt normal lung growth and development. However, the mechanism of hyperoxia-i...

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Detalles Bibliográficos
Autores principales: Chen, Hsing-Jin, Chiang, Bor-Luen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624932/
https://www.ncbi.nlm.nih.gov/pubmed/26509921
http://dx.doi.org/10.1371/journal.pone.0140343