Cargando…

PTPN13 and β-Catenin Regulate the Quiescence of Hematopoietic Stem Cells and Their Interaction with the Bone Marrow Niche

The regulation of hematopoietic stem cells (HSCs) depends on the integration of the multiple signals received from the bone marrow niche. We show the relevance of the protein tyrosine phosphatase PTPN13 and β-catenin as intracellular signaling molecules to control HSCs adhesiveness, cell cycling, an...

Descripción completa

Detalles Bibliográficos
Autores principales: López-Ruano, Guillermo, Prieto-Bermejo, Rodrigo, Ramos, Teresa L., San-Segundo, Laura, Sánchez-Abarca, Luis Ignacio, Sánchez-Guijo, Fermín, Pérez-Simón, José Antonio, Sánchez-Yagüe, Jesús, Llanillo, Marcial, Hernández-Hernández, Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624939/
https://www.ncbi.nlm.nih.gov/pubmed/26344907
http://dx.doi.org/10.1016/j.stemcr.2015.08.003

Ejemplares similares