Ras Oncogene-Mediated Progressive Silencing of Extracellular Superoxide Dismutase in Tumorigenesis

Extracellular superoxide dismutase (SOD3) is a secreted enzyme that uses superoxide anion as a substrate in a dismutase reaction that results in the formation of hydrogen peroxide. Both of these reactive oxygen species affect growth signaling in cells. Although SOD3 has growth-supporting characteris...

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Detalles Bibliográficos
Autores principales: Cammarota, Francesca, de Vita, Gabriella, Salvatore, Marco, Laukkanen, Mikko O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624945/
https://www.ncbi.nlm.nih.gov/pubmed/26550576
http://dx.doi.org/10.1155/2015/780409

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