Cargando…

Monitoring Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes with Genetically Encoded Calcium and Voltage Fluorescent Reporters

The advent of the human-induced pluripotent stem cell (hiPSC) technology has transformed biomedical research, providing new tools for human disease modeling, drug development, and regenerative medicine. To fulfill its unique potential in the cardiovascular field, efficient methods should be develope...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shinnawi, Rami, Huber, Irit, Maizels, Leonid, Shaheen, Naim, Gepstein, Amira, Arbel, Gil, Tijsen, Anke J., Gepstein, Lior
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624957/ https://www.ncbi.nlm.nih.gov/pubmed/26372632 http://dx.doi.org/10.1016/j.stemcr.2015.08.009

Ejemplares similares

Human Induced Pluripotent Stem Cell-Derived Cardiac Cell Sheets Expressing Genetically Encoded Voltage Indicator for Pharmacological and Arrhythmia Studies
por: Shaheen, Naim, et al.
Publicado: (2018)

Characterization of the mechanism by which a nonsense variant in RYR2 leads to disordered calcium handling
por: Hopton, Claire, et al.
Publicado: (2022)

Calcium Handling in Human Induced Pluripotent Stem Cell Derived Cardiomyocytes
por: Itzhaki, Ilanit, et al.
Publicado: (2011)

Optogenetic Control of Human Induced Pluripotent Stem Cell‐Derived Cardiac Tissue Models
por: Gruber, Amit, et al.
Publicado: (2022)

Optogenetic modulation of cardiac action potential properties may prevent arrhythmogenesis in short and long QT syndromes
por: Gruber, Amit, et al.
Publicado: (2021)

Utilizing human induced pluripotent stem cells to study atrial arrhythmias in the short QT syndrome
por: Shiti, Assad, et al.
Publicado: (2023)

Single-Cell Mechanical Analysis of Human Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Testing and Pathophysiological Studies
por: Ballan, Nimer, et al.
Publicado: (2020)

Reply to ‘Are atrial human pluripotent stem cell-derived cardiomyocytes ready to identify drugs that beat atrial fibrillation?’
por: Shiti, Assad, et al.
Publicado: (2021)

Generating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes
por: Goldfracht, Idit, et al.
Publicado: (2020)

shRNAs Targeting a Common KCNQ1 Variant Could Alleviate Long-QT1 Disease Severity by Inhibiting a Mutant Allele
por: Cócera-Ortega, Lucía, et al.
Publicado: (2022)

Rapid Cellular Phenotyping of Human Pluripotent Stem Cell-Derived Cardiomyocytes using a Genetically Encoded Fluorescent Voltage Sensor
por: Leyton-Mange, Jordan S., et al.
Publicado: (2014)

Leaf senescence - not just a 'wear and tear' phenomenon
por: Gepstein, Shimon
Publicado: (2004)

Obesity as the Main Risk Factor for Metabolic Syndrome in Children
por: Gepstein, Vardit, et al.
Publicado: (2019)

Fluorescence lifetime predicts performance of voltage sensitive fluorophores in cardiomyocytes and neurons
por: Boggess, Steven C., et al.
Publicado: (2020)

Quaking regulates circular RNA production in cardiomyocytes
por: Montañés-Agudo, Pablo, et al.
Publicado: (2023)

Bilateral simultaneous central retinal vein occlusion in hyperviscosity retinopathy treated with systemic immunosuppressive therapy only
por: Blau-Most, Michal, et al.
Publicado: (2018)

Left Ventricular Systolic Dysfunction Due to Atrial Fibrillation: Clinical and Echocardiographic Predictors
por: Marcusohn, Erez, et al.
Publicado: (2021)

The role of genetic testing in the prevention, diagnosis, and prognosis of sudden cardiac arrest in children
por: Blich, Miry, et al.
Publicado: (2023)

Red Fluorescent Genetically Encoded Voltage Indicators with Millisecond Responsiveness
por: Kost, Liubov A., et al.
Publicado: (2019)

Titin Circular RNAs Create a Back-Splice Motif Essential for SRSF10 Splicing
por: Tijsen, Anke J., et al.
Publicado: (2021)

Acute posterior multifocal placoid pigment epitheliopathy associated with CN III palsy
por: Pillar, Shani, et al.
Publicado: (2021)

Simultaneous Widefield Voltage and Dye-Free Optical Mapping Quantifies Electromechanical Waves in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: Liu, Wei, et al.
Publicado: (2023)

Engineering of a Genetically Encodable Fluorescent Voltage Sensor Exploiting Fast Ci-VSP Voltage-Sensing Movements
por: Lundby, Alicia, et al.
Publicado: (2008)

A Fluorescent, Genetically-Encoded Voltage Probe Capable of Resolving Action Potentials
por: Barnett, Lauren, et al.
Publicado: (2012)

Mechanistic Studies of the Genetically Encoded Fluorescent Protein Voltage Probe ArcLight
por: Han, Zhou, et al.
Publicado: (2014)

Minimally invasive treatment of lumbar spinal stenosis with a novel interspinous spacer
por: Shabat, Shay, et al.
Publicado: (2011)

A compatible interaction of Alternaria brassicicola with Arabidopsis thaliana ecotype DiG: evidence for a specific transcriptional signature
por: Mukherjee, Arup K, et al.
Publicado: (2009)

Normal Performance in Non-Visual Social Cognition Tasks in Women with Turner Syndrome
por: Anaki, David, et al.
Publicado: (2018)

Insertion of the voltage-sensitive domain into circularly permuted red fluorescent protein as a design for genetically encoded voltage sensor
por: Kost, Liubov A., et al.
Publicado: (2017)

Type of Anemia, Chronic Non-cardiovascular Illnesses, and Outcomes of Patients with ST-segment Elevation Myocardial Infarction
por: Menzely, Tomer, et al.
Publicado: (2020)

The Use of Ratiometric Fluorescence Measurements of the Voltage Sensitive Dye Di-4-ANEPPS to Examine Action Potential Characteristics and Drug Effects on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: Hortigon-Vinagre, M. P., et al.
Publicado: (2016)

Human Cardiomyocyte Progenitor Cells in Co-culture with Rat Cardiomyocytes Form a Pro-arrhythmic Substrate: Evidence for Two Different Arrhythmogenic Mechanisms
por: Smit, Nicoline W., et al.
Publicado: (2017)

Peer Learning and Support of Technology in an Undergraduate Biology Course to Enhance Deep Learning
por: Tsaushu, Masha, et al.
Publicado: (2012)

Herpesvirus-Mediated Delivery of a Genetically Encoded Fluorescent Ca(2+) Sensor to Canine Cardiomyocytes
por: Prorok, János, et al.
Publicado: (2009)

Modulating the Voltage-sensitivity of a Genetically Encoded Voltage Indicator
por: Jung, Arong, et al.
Publicado: (2017)

The Third Intron of the Interferon Regulatory Factor-8 Is an Initiator of Repressed Chromatin Restricting Its Expression in Non-Immune Cells
por: Khateb, Mamduh, et al.
Publicado: (2016)

Expanding the family of genetically encoded voltage indicators with a candidate Heliorhodopsin exhibiting near-infrared fluorescence
por: Ganapathy, Srividya, et al.
Publicado: (2023)

Endovascular treatment of an open cervical fracture with carotid artery tear
por: Witz, Misha, et al.
Publicado: (2006)

Clinical and genetic characteristics and course of congenital long QT syndrome: A ten-year single center experience
por: Blich, M, et al.
Publicado: (2023)

Co-culture of induced pluripotent stem cells with cardiomyocytes is sufficient to promote their differentiation into cardiomyocytes
por: Chu, Axel J., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vmqvfvcn909b3klm146bho7d0c