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Mucosal Immunogenicity of Genetically Modified Lactobacillus acidophilus Expressing an HIV-1 Epitope within the Surface Layer Protein

Surface layer proteins of probiotic lactobacilli are theoretically efficient epitope-displaying scaffolds for oral vaccine delivery due to their high expression levels and surface localization. In this study, we constructed genetically modified Lactobacillus acidophilus strains expressing the membra...

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Detalles Bibliográficos
Autores principales:	Kajikawa, Akinobu, Zhang, Lin, LaVoy, Alora, Bumgardner, Sara, Klaenhammer, Todd R., Dean, Gregg A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624987/ https://www.ncbi.nlm.nih.gov/pubmed/26509697 http://dx.doi.org/10.1371/journal.pone.0141713

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