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Activin/Nodal Signaling Supports Retinal Progenitor Specification in a Narrow Time Window during Pluripotent Stem Cell Neuralization
Retinal progenitors are initially found in the anterior neural plate region known as the eye field, whereas neighboring areas undertake telencephalic or hypothalamic development. Eye field cells become specified by switching on a network of eye field transcription factors, but the extracellular cues...
Autores principales: | Bertacchi, Michele, Lupo, Giuseppe, Pandolfini, Luca, Casarosa, Simona, D’Onofrio, Mara, Pedersen, Roger A., Harris, William A., Cremisi, Federico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624997/ https://www.ncbi.nlm.nih.gov/pubmed/26388287 http://dx.doi.org/10.1016/j.stemcr.2015.08.011 |
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