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Critical role of c-jun N-terminal protein kinase in promoting mitochondrial dysfunction and acute liver injury

The mechanism by which c-Jun N-terminal protein kinase (JNK) promotes tissue injury is poorly understood. Thus we aimed at studying the roles of JNK and its phospho-target proteins in mouse models of acute liver injury. Young male mice were exposed to a single dose of CCl(4) (50 mg/kg, IP) and eutha...

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Detalles Bibliográficos
Autores principales:	Jang, Sehwan, Yu, Li-Rong, Abdelmegeed, Mohamed A., Gao, Yuan, Banerjee, Atrayee, Song, Byoung-Joon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625008/ https://www.ncbi.nlm.nih.gov/pubmed/26491845 http://dx.doi.org/10.1016/j.redox.2015.09.040

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