Long Withdrawal of Methylphenidate Induces a Differential Response of the Dopaminergic System and Increases Sensitivity to Cocaine in the Prefrontal Cortex of Spontaneously Hypertensive Rats

Methylphenidate (MPD) is one of the most prescribed drugs for alleviating the symptoms of Attention Deficit/Hyperactivity Disorder (ADHD). However, changes in the molecular mechanisms related to MPD withdrawal and susceptibility to consumption of other psychostimulants in normal individuals or indiv...

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Detalles Bibliográficos
Autores principales: dos Santos Pereira, Maurício, Sathler, Matheus Figueiredo, Valli, Thais da Rosa, Marques, Richard Souza, Ventura, Ana Lucia Marques, Peccinalli, Ney Ronner, Fraga, Mabel Carneiro, Manhães, Alex C., Kubrusly, Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625026/
https://www.ncbi.nlm.nih.gov/pubmed/26509840
http://dx.doi.org/10.1371/journal.pone.0141249

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