Cargando…
Data in support of substrate flexibility of a mutated acyltransferase domain and implications for polyketide biosynthesis
Enzyme-directed mutasynthesis is an emerging strategy for the targeted derivatization of natural products. Here, data on the synthesis of malonic acid derivatives for feeding studies in Saccharopolyspora erythraea , the mutagenesis of DEBS and bioanalytical data on the experimental investigation of...
Autores principales: | Klopries, Stephan, Bravo-Rodriguez, Kenny, Koopmans, Kyra R.M., Sundermann, Uschi, Yahiaoui, Samir, Arens, Julia, Kushnir, Susanna, Sanchez-Garcia, Elsa, Schulz, Frank |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625040/ https://www.ncbi.nlm.nih.gov/pubmed/26587559 http://dx.doi.org/10.1016/j.dib.2015.09.052 |
Ejemplares similares
-
Quantification of N-acetylcysteamine activated methylmalonate incorporation into polyketide biosynthesis
por: Klopries, Stephan, et al.
Publicado: (2013) -
Expanding Extender
Substrate Selection for Unnatural
Polyketide Biosynthesis by Acyltransferase Domain Exchange within
a Modular Polyketide Synthase
por: Englund, Elias, et al.
Publicado: (2023) -
Engineering the acyltransferase domain of epothilone polyketide synthase to alter the substrate specificity
por: Wang, Huimin, et al.
Publicado: (2021) -
Acyltransferases as Tools for Polyketide Synthase Engineering
por: Musiol-Kroll, Ewa Maria, et al.
Publicado: (2018) -
Computationally-guided exchange of substrate selectivity motifs in a modular polyketide synthase acyltransferase
por: Kalkreuter, Edward, et al.
Publicado: (2021)