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Enhanced Production of Adenosine Triphosphate by Pharmacological Activation of Adenosine Monophosphate-Activated Protein Kinase Ameliorates Acetaminophen-Induced Liver Injury

The hepatic cell death induced by acetaminophen (APAP) is closely related to cellular adenosine triphosphate (ATP) depletion, which is mainly caused by mitochondrial dysfunction. Adenosine monophosphate (AMP)-activated protein kinase (AMPK) is a key sensor of low energy status. AMPK regulates metabo...

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Detalles Bibliográficos
Autores principales:	Hwang, Jung Hwan, Kim, Yong-Hoon, Noh, Jung-Ran, Choi, Dong-Hee, Kim, Kyoung-Shim, Lee, Chul-Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625065/ https://www.ncbi.nlm.nih.gov/pubmed/26434492 http://dx.doi.org/10.14348/molcells.2015.0072

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