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High-Dose Nicotinamide Suppresses ROS Generation and Augments Population Expansion during CD8(+) T Cell Activation

During T cell activation, mitochondrial content increases to meet the high energy demand of rapid cell proliferation. With this increase, the level of reactive oxygen species (ROS) also increases and causes the rapid apoptotic death of activated cells, thereby facilitating T cell homeostasis. Nicoti...

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Detalles Bibliográficos
Autores principales:	Choi, Ho Jin, Jang, So-Young, Hwang, Eun Seong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625074/ https://www.ncbi.nlm.nih.gov/pubmed/26442863 http://dx.doi.org/10.14348/molcells.2015.0168

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