Entropic analysis reveals a connection between the recurrence of cancer and chemotherapy

In this study, we proposed an entropic analysis to overcome limitations of conventional statistical methods to analyze clinical data for cancer patients who experienced relapse of tumors following chemotherapy. We have applied this entropic method to reveal potential mechanisms that lead to a relaps...

Descripción completa

Detalles Bibliográficos
Autores principales: Tseng, Chih-Yuan, Tuszynski, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625121/
https://www.ncbi.nlm.nih.gov/pubmed/26586992
http://dx.doi.org/10.1016/j.sjbs.2015.05.005
_version_ 1782397936442802176
author Tseng, Chih-Yuan
Tuszynski, Jack
author_facet Tseng, Chih-Yuan
Tuszynski, Jack
author_sort Tseng, Chih-Yuan
collection PubMed
description In this study, we proposed an entropic analysis to overcome limitations of conventional statistical methods to analyze clinical data for cancer patients who experienced relapse of tumors following chemotherapy. We have applied this entropic method to reveal potential mechanisms that lead to a relapse of Wilms’ tumor in pediatric patients. Results indicate β-tubulin isotype III up-regulation is likely the primary cause of the relapse.
format Online
Article
Text
id pubmed-4625121
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-46251212015-11-19 Entropic analysis reveals a connection between the recurrence of cancer and chemotherapy Tseng, Chih-Yuan Tuszynski, Jack Saudi J Biol Sci Original Article In this study, we proposed an entropic analysis to overcome limitations of conventional statistical methods to analyze clinical data for cancer patients who experienced relapse of tumors following chemotherapy. We have applied this entropic method to reveal potential mechanisms that lead to a relapse of Wilms’ tumor in pediatric patients. Results indicate β-tubulin isotype III up-regulation is likely the primary cause of the relapse. Elsevier 2015-11 2015-05-13 /pmc/articles/PMC4625121/ /pubmed/26586992 http://dx.doi.org/10.1016/j.sjbs.2015.05.005 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Tseng, Chih-Yuan
Tuszynski, Jack
Entropic analysis reveals a connection between the recurrence of cancer and chemotherapy
title Entropic analysis reveals a connection between the recurrence of cancer and chemotherapy
title_full Entropic analysis reveals a connection between the recurrence of cancer and chemotherapy
title_fullStr Entropic analysis reveals a connection between the recurrence of cancer and chemotherapy
title_full_unstemmed Entropic analysis reveals a connection between the recurrence of cancer and chemotherapy
title_short Entropic analysis reveals a connection between the recurrence of cancer and chemotherapy
title_sort entropic analysis reveals a connection between the recurrence of cancer and chemotherapy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625121/
https://www.ncbi.nlm.nih.gov/pubmed/26586992
http://dx.doi.org/10.1016/j.sjbs.2015.05.005
work_keys_str_mv AT tsengchihyuan entropicanalysisrevealsaconnectionbetweentherecurrenceofcancerandchemotherapy
AT tuszynskijack entropicanalysisrevealsaconnectionbetweentherecurrenceofcancerandchemotherapy

Ejemplares similares