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High efficacy vasopermeability drug candidates identified by screening in an ex ovo chorioallantoic membrane model
The use of rodent models to evaluate efficacy during testing is accompanied by significant economic and regulatory hurdles which compound the costs of screening for promising drug candidates. Vasopermeation Enhancement Agents (VEAs) are a new class of biologics that are designed to increase the upta...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625159/ https://www.ncbi.nlm.nih.gov/pubmed/26510887 http://dx.doi.org/10.1038/srep15756 |