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Nanoparticle Targeting and Cholesterol Flux Through Scavenger Receptor Type B-1 Inhibits Cellular Exosome Uptake

Exosomes are nanoscale vesicles that mediate intercellular communication. Cellular exosome uptake mechanisms are not well defined partly due to the lack of specific inhibitors of this complex cellular process. Exosome uptake depends on cholesterol-rich membrane microdomains called lipid rafts, and c...

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Detalles Bibliográficos
Autores principales:	Plebanek, Michael P., Mutharasan, R. Kannan, Volpert, Olga, Matov, Alexandre, Gatlin, Jesse C., Thaxton, C. Shad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625174/ https://www.ncbi.nlm.nih.gov/pubmed/26511855 http://dx.doi.org/10.1038/srep15724

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