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Putative Breast Cancer Driver Mutations in TBX3 Cause Impaired Transcriptional Repression
The closely related T-box transcription factors TBX2 and TBX3 are frequently overexpressed in melanoma and various types of human cancers, in particular, breast cancer. The overexpression of TBX2 and TBX3 can have several cellular effects, among them suppression of senescence, promotion of epithelia...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625211/ https://www.ncbi.nlm.nih.gov/pubmed/26579496 http://dx.doi.org/10.3389/fonc.2015.00244 |