Prior infection with Type A Francisella tularensis antagonizes the pulmonary transcriptional response to an aerosolized Toll-like receptor 4 agonist

BACKGROUND: Francisella infection attenuates immune cell infiltration and expression of selected pro-inflammatory cytokines in response to endogenous LPS, suggesting the bacteria is actively antagonizing at least some part of the response to Toll-like receptor 4 (TLR4) engagement. The ability of dif...

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Detalles Bibliográficos
Autores principales: Walters, Kathie-Anne, Olsufka, Rachael, Kuestner, Rolf E., Wu, Xiagang, Wang, Kai, Skerrett, Shawn J., Ozinsky, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625460/
https://www.ncbi.nlm.nih.gov/pubmed/26510639
http://dx.doi.org/10.1186/s12864-015-2022-2

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